blue neurons illustration

Articles

  1. Cummings, K.J., J.C. Leiter, F.L. Trachtenberg, B.W. Okaty, R.A. Darnall, E.A. Haas, R.M. Harper, E.E. Nattie, H.F. Krous, O.J. Mena, G.B. Richerson, S.M. Dymecki, H.C. Kinney, R.L. Haynes. Altered 5-HT2A/C receptor binding in the medulla oblongata in the sudden infant death syndrome (SIDS): Part II. Age-associated alterations in serotonin receptor binding profiles within medullary nuclei supporting cardiorespiratory homeostasis. Journal of Neuropathology and Experimental Neurology. (in press), 2024.
  2. Richerson, G.B. Divergent causes and convergent mechanisms of SUDEP. Annals of Neurology (in press), 2023.
  3. Smith, J., G. Richerson, H. Kouchi, F. Duprat, M. Mantegazza, L. Bezin & S. Rheims. Are we there yet?: A critical evaluation of SUDEP models. Epilepsia (in revision), 2023.
  4. Sainju, R.K., D.N. Dragon, H.B. Winnike, L.B. Vilella, X. Li, S. Lhatoo, P. Ten Eyck, L.H. Wendt, G.B. Richerson & B.K. Gehlbach. Interictal respiratory variability predicts severity of hypoxemia after generalized convulsive seizures. Epilepsia (in press), 2023.
  5. Harmata, G.I.S., A.E. Rhone, C.K. Kovach, S. Kumar, M.R. Mowla, R.K. Sainju, Y. Nagahama, H. Oya, B.K. Gehlbach, M.A. Ciliberto, R.N. Mueller, H. Kawasaki, K.T.S. Pattinson, K. Simonyan, P.W. Davenport, M.A. Howard, M. Steinschneider, A.C. Chan, G.B. Richerson, J.A. Wemmie & B.J. Dlouhy. Failure to breathe persists without air hunger or alarm following amygdala seizures. JCI Insight (in press), 2023.
  6. Teran, F.A., R.K. Sainju, E. Bravo, J. Wagnon, Y. Kim, A. Granner, B.K. Gehlbach & G.B. Richerson. Seizures cause prolonged impairment of ventilation, CO2 chemoreception and thermoregulation. J Neurosci 43(27):4959–4971, 2023. [PMID: 37344924]. [Selected as “Noteworthy” for J Neurosci Featured Research page.]
  7. Giannoni, A., C. Borrelli, F. Gentile, P. Sciarrone, J. Spießhöfer, M. Piepoli, G.B. Richerson, J.S. Floras, A.J.S. Coats, S. Javaheri, M. Emdin, C. Passino. Autonomic and respiratory consequences of altered chemoreflex function: Clinical and therapeutic implications in cardiovascular diseases. Euro J Heart Failure (5):642-656, 2023.
  8. Sainju, RK, DN Dragon, HB Winnike, PT Eyck, MA Granner, BK Gehlbach, GB Richerson. Use of Fluoxetine to Augment the Inter-Ictal Hypercapnic Ventilatory Response in Patients with Epilepsy: A Pilot Study. Neurol India (neurologyindia.com), 2022.
  9. Teran, F.A., E. Bravo & G.B. Richerson. Sudden unexpected death in epilepsy: Respiratory mechanisms. In: Chen R and Guyenet PG (Eds). Respiratory Neurobiology: Physiology and Clinical Disorders, Part 2. San Diego: Elsevier BV, 2022. [PMC10191258]
  10. Crotts, M.S., Y. Kim, E. Bravo, G.B. Richerson & F.A. Teran. A ketogenic diet protects DBA/1 and Scn1aR1407X/+ mice against seizure-induced respiratory arrest independent of ketosis. Epi & Behav 124:108334, 2021. [PMID: 34600281]
  11. Sainju, R., D. Dragon, H. Winnike, P. Ten Eyck, M. Granner, B. Gehlbach, G.B. Richerson. Hypercapnic ventilatory response in epilepsy patients treated with VNS: a case-control study. Epilepsia 62:e140–e146, 2021.
  12. Zhao, X., L. Vilella, L. Zhu, S. Rani, J.P. Hampson, J. Hampson, N.J. Hupp, R.K. Sainju, D. Friedman, M. Nei,  C. Scott, L. Allen, B.K. Gehlbach,  S. Schuele, R.M. Harper, B. Diehl, L.M. Bateman, O. Devinsky, G.B. Richerson, G. Zhang, S.D. Lhatoo & N. Lacuey. Automated Analysis of Risk factors for Postictal Generalized EEG Suppression. Front Neurol 12:669517, 2021. [PMID: 34046007] PMCID: PMC8148040.
  13. Wenker, I.C., F.A. Teran, E.R. Wengert, P.K. Wagley, P.S. Panchal, E.A. Blizzard, P. Saraf, J.L. Wagnon, H.P. Goodkin, M.H. Meisler, G.B. Richerson, & M.K. Patel. Postictal sudden death is associated with tonic phase apnea in a mouse model of SUDEP due to an Scn8a mutation. Ann Neurol, 89(5):1023-1035, 2021. [PMID: 33604927]
  14. Ochoa-Urrea, M., N. Lacuey Lecumberri, L. Vilella, L. Zhu, S. Omidi, M.R. Sandhya Rani, J.P. Hampson, M. Dayyani, J.S. Hampson, N.J. Hupp, S. Tao, R.K. Sainju, D. Friedman, M. Nei, C. Scott, L.A. Allen, B.K. Gehlbach, V. Reick-Mitrisin, S. Schuele, J.A. Ogren, R.M. Harper, B. Diehl, L. Bateman, O. Devinsky, G.B. Richerson, G.-Q. Zhang, S. Lhatoo. Seizure clusters, seizure severity markers and SUDEP risk. Front Neurol 12:643916, 2021. [PMID: 33643216].
  15. Vilella, L., N. Lacuey, J.P. Hampson, L. Zhu, S. Omidi, M. Ochoa-Urrea, S. Tao, M.R. Sandhya Rani, R.K. Sainju, D. Friedman,  M. Nei, K. Strohl, C. Scott, L. Allen, B.K. Gehlbach, N.J. Hupp, J.S. Hampson, N. Shafiabadi, X. Zhao, V. Reick-Mitrisin, S. Schuele, J. Ogren, R.M. Harper, B. Diehl, L.M. Bateman, O. Devinsky, G.B. Richerson, P. Ryvlin, G.Q. Zhang & S.D. Lhatoo.  Association of peri-ictal brainstem posturing with seizure severity and breathing compromise in patients with generalized convulsive seizures. Neurology, 96(3):e352-e365, 2021. [PMID: 33268557].
  16. Marincovich, A., E. Bravo, B. Dlouhy & G.B. Richerson. Amygdala lesions reduce seizure-induced respiratory arrest in DBA/1 mice. Epi & Behav, 121(PtB):106440, 2021. [PMID: 31399338] PMCID: 7474464.
  17. Giannoni, A., C. Borrelli, G. Mirizzi, G. Richerson, M. Emdin & C. Passino. Benefit of buspirone on chemoreflex and central apnoeas in heart failure: a randomized controlled crossover trial. European Journal of Heart Failure, 23(2):312-320, 2021. [PMID: 32441857].
  18. Avraam, J., Y. Wu & G.B. Richerson. Perinatal nicotine reduces chemosensitivity of medullary 5-HT neurons after maturation in culture. Neurosci, 446:80-93, 2020. [PMID: 32818601] PMCID: PMC7530107.
  19. Rhone, A.E., C.K. Kovach, G.I.S. Harmata, A.W. Sullivan, D. Tranel, M. Ciliberto, M. Howard, G.B. Richerson, M. Steinschneider, J. Wemmie & B. Dlouhy. A human amygdala site that inhibits respiration and elicits apnea in pediatric epilepsy. JCI Insight 5(6):e134852, 2020. [PMID:32163374] PMCID: PMC 7213805.
  20. Murugesan, A., M.R. Sandhya Rani, L. Vilella, N. Lacuey, J.P. Hampson, C.L. Faingold, D. Friedman, O. Devinsky, R.K. Sainju, S. Schuele, B. Diehl, M. Nei, R.M. Harper, L.M. Bateman, G.B. Richerson & S.D. Lhatoo. Post-ictal serotonin levels are associated with peri-ictal apnea. Neurology, 93(15):e1485-e1494, 2019. [PMID: 31484709] PMCID: PMC7010327.
  21. Lacuey, N., R. Martins, L. Vilella, J.P. Hampson, M.R. Sandhya Rani, K. Strohl, A. Zaremba, R.K. Sainju, D. Friedman, M. Nei, C. Scott, B.K. Gehlbach, N.J. Hupp, S. Schuele, J. Ogren, R.M. Harper, L. Allen, B. Diehl, L. Bateman, O. Devinsky, G.B. Richerson & S. Lhatoo. The association of serotonin reuptake inhibitors and benzodiazepines with ictal central apnea. Epilepsy & Behavior, 98(Pt A):73-79, 2019. [PMID: 31301453]
  22. Guo, D.F., Z. Lin, Y. Wu, C. Searby, D.R. Thedens, G.B. Richerson, Y.M. Usachev, J.L. Grobe1, V.C. Sheffield & K. Rahmouni. The BBSome in POMC and AgRP neurons is necessary for body weight regulation and sorting of metabolic receptors. Diabetes, 68(8):1591-1603, 2019. [PMID: 31127052] PMCID: PMC6692817.
  23. Wu, Y., K. Proch, F.A. Teran, R. Lechtenberg, H. Kothari & G.B. Richerson.  Input from serotonin neurons contributes to chemosensitivity of Phox2b expressing retrotrapezoid neurons. J Physiol, 597(10):2741-2766, 2019. [PMID: 30866045] PMCID: PMC6826216.
  24. Teran, F.A., Y. Kim, M. Crotts, E. Bravo, K. Emaus & G.B. Richerson. Time of day and a ketogenic diet influence susceptibility to SUDEP in Scn1aR1407X/+ mice. Front Neurol, 10:278, 2019. [PMID: 30984098] PMCID: PMC6449461.
  25. Vilella, L., N. Lacuey, J.P. Hampson, M.R. Sandhya Rani, K. Loparo, R.K. Sainju, D. Friedman,  M. Nei, K. Strohl, C. Scott, B.K Gehlbach, B. Zonjy, N.J. Hupp, A. Zaremba, N. Shafiabadi, X. Zhao, V. Reick-Mitrisin, S. Schuele, J. Ogren, R.M. Harper, B. Diehl, L.M. Bateman, O. Devinsky, G.B. Richerson, A. Tanner, C. Tatsuoka & S.D. Lhatoo. Incidence, recurrence and risk factors for peri-ictal central apnea and sudden unexpected death in epilepsy. Front Neurol, 10(166):1-13, 2019. [PMID:30890997] PMCID: PMC6413671.
  26. Sainju, R.K., D.N. Dragon, H.B. Winnike, M.B. Nashelsky, M.A. Granner, B.K. Gehlbach* & G.B. Richerson*.  Ventilatory response to CO2 in patients with epilepsy. Epilepsia, 60(3):508-517, 2019. [PMID:30756391] PMCID: PMC6401234.
  27. Vilella, L., N. Lacuey, J.P. Hampson, R.K. Sainju, D. Friedman, M. Nei1, K. Strohl, C. Scott, B.K. Gehlbach, B. Zonjy, N.J. Hupp, A. Zaremba, M.R. Sandhya Rani, N. Shafiabadi, X. Zhao, V. Reick-Mitrisin, S. Schuele, J. Ogren, R.M. Harper, B. Diehl, L. Bateman, O. Devinsky, G.B. Richerson, P. Ryvlin, S.D. Lhatoo. Post-convulsive central apnea as a biomarker for Sudden Unexpected Death in Epilepsy (SUDEP). Neurology, 92(3):e171-e182, 2019. [PMID: 30568003] PMCID: PMC6340388.
  28. Donner, E.J., T.F. Stanton & G.B. Richerson. Summary of the PAME 2018 Meeting. Epilepsy Currents 18(6):398-399, 2018. [PMID: 30568561] PMCID: PMC6278740.
  29. Gehlbach, B.K., R.K. Sainju, D.K. Tadlock, D.N. Dragon, M.A. Granner & G.B. Richerson. Tolerability of a comprehensive cardiorespiratory monitoring protocol in an epilepsy monitoring unit. Epilepsy & Behavior, 85:173-176, 2018. [PMID: 29981497] PMCID: PMC6214684.
  30. Chae, W.S., S. Choi, D. Sugiyama, G.B Richerson, T.J. Brennan & S. Kang. The effect of thoracic epidural anesthesia in a rat model of phrenic motor inhibition after upper abdominal surgery.  Anesthesiology, 129(4):791-807, 2018. [PMID: 29952817] PMCID: PMC6148380.
  31. Murugesan, A., M.R. Sandhya Rani, J. Hampson, B. Zonjy, N. Laucey, C.L. Faingold, D. Friedman, O. Devinsky, R.K. Sainju, S. Schuele, B. Diehl, M. Nei, R.M. Harper, L.M. Bateman, G.B. Richerson & S.D. Lhatoo.  Serum Serotonin Levels in Patients with Epileptic Seizures.  Epilepsia, 59:e91-e97, 2018. [PMID: 29771456] PMCID: PMC6141199.
  32. Lacuey, N., J. Hampson, B. Zonjy, M.R.S. Rani, A. Zaremba, R.K. Sainju, B.K. Gehlbach, S. Schuele, D. Friedman, M. Nei, R. Harper, L. Allen, B. Diehl, J. Millichap, L. Bateman, M. Granner, D. Dragon, G.B. Richerson, & S. Lhatoo.  The incidence and significance of peri-ictal apnea in epileptic seizures.  Epilepsia, 59(3):573-582, 2018. [PMID: 29336036] PMCID: PMC6103445.
  33. Kim, Y.J., E. Bravo, C.K. Thirnbeck, L.A. Smith-Mellecker, S.H. Kim, B.K. Gehlbach, L. Laux, D.R. Nordli, Jr. & G.B. Richerson. Severe peri-ictal respiratory dysfunction is common in Dravet Syndrome.  J Clinical Investigation, 128(3):1141-1153, 2018. [PMID:     29329111] PMCID: PMC5824857.
  34. Massey, C.A. & G.B. Richerson.  Isoflurane, ketamine-xylazine, and urethane markedly alter breathing even at sub-therapeutic doses.  J Neurophysiol, 118(4):2389-2401, 2017. [PMID: 28747467] PMCID: PMC5646190.
  35. Dlouhy, B.J., M.A. Ciliberto, C.L. Cifra, P.A. Kirby, D.L. Schrock, M. Nashelsky, & G.B. Richerson.  Unexpected death in a child with complex febrile seizures – similar pathophysiology to sudden unexpected death in epilepsy (SUDEP)?  Frontiers in Neurology, 8:21, 2017. [PMID: 28203222] PMCID: PMC5286923.
  36. Ransom, C.B., Z. Ye, W.J. Spain & G.B. Richerson.  Modulation of tonic GABA currents by connexin hemichannel and anion channel antagonists.  Neurochem Res, 42(9):2551-2559, 2017. [PMID: 28401401]
  37. Cerpa, V.J., Y. Wu, E.U. Bravo, F.A. Teran, R.S. Flynn & G.B. Richerson. Medullary 5-HT neurons: Switch from respiratory drive to chemoreception during postnatal development. Neurosci, 344:1-14, 2017. [PMID: 27619736] PMCID: PMC530367.
  38. Buchanan, G.F. & G.B. Richerson.  Epilepsy: A dietary supplement for SUDEP prevention?  Nature Rev Neurol, 12(9):495-6, 2016. [PMID: 27514288]
  39. Devinsky, O., D.C. Hesdorffer, D. Thurman, S. Lhatoo, G.B. Richerson. Sudden Unexpected Death in Epilepsy: Epidemiology, Mechanisms & Prevention. Lancet Neurology, 15(10):1075-88, 2016. [PMID: 27571159]
  40. Zhan, Q., G. Buchanan, J. Motelow, J. Andrews, P. Vitkovskiy, W. Chen, F. Serout, A. Gummadavelli, A. Kundishora, M. Furman, W. Li, X. Bo, G.B. Richerson, and H. Blumenfeld.  Impaired serotonergic brainstem function during and following seizures. J Neurosci, 36(9):2711-22, 2016. [PMID: 26937010] PMCID: PMC487914.
  41. Richerson, G.B., D. Boison, C. Faingold & P. Ryvlin.  SUDEP: From unwitnessed fatality to witnessed rescue: pharmacological intervention.  Epilepsia, 57(Suppl 1):35-45, 2016. [PMID: 26749015] PMCID: PMC4890608.
  42. Lhatoo, S., J. Noebels, V. Whittemore, and The NINDS Center for SUDEP Research.  Sudden Unexpected Death in Epilepsy (SUDEP): Identifying Risk and Preventing Mortality.  Epilepsia, 56(11):1700-6, 2015. [PMID: 26494436] PMCID: PMC4852129.
  43. Murray, N.M., G.F. Buchanan & G.B. Richerson. Insomnia caused by serotonin depletion is due to hypothermia. Sleep, 38(12):1985-93, 2015. [PMID: 26194567] PMCID: PMC4667392.
  44. Dlouhy, B.J., B.K. Gehlbach & G.B. Richerson. Sudden unexpected death in epilepsy (SUDEP): basic mechanisms and clinical implications for prevention. J Neurol Neurosurg Psych, 87(4):402-13, 2015. [PMID: 26979537]
  45. Cerpa, V.J., M.L. Aylwin, S. Beltrán-Castillo, E.U. Bravo, I.R. Llona, G.B. Richerson & J.L. Eugenín.  Alteration of neonatal raphe neurons by prenatal-perinatal nicotine: Meaning for Sudden Infant Death Syndrome. Am J Respir Cell Mol Biol, 53(4):489-99, 2015. [PMID: 25695895] PMCID: PMC4742896.
  46. Dlouhy, B.J., B.K. Gehlbach, C.J. Kreple, H. Kawasaki, H. Oya, C. Buzza, M.A. Granner, M.J. Welsh, M.A. Howard III, J.A. Wemmie* and G.B. Richerson*. Breathing inhibited when seizures spread to the amygdala and upon amygdala stimulation. J Neurosci, 35(28):10281-9, 2015. [PMID: 26180203] PMCID: PMC4502266.
  47. Buchanan, G.F., H. Smith, A. MacAskill & G.B. Richerson.  5-HT2A receptor activation is necessary for CO2-induced arousal. J Neurophysiol, 114(1):233-43, 2015. [PMID: 25925320] PMCID: PMC4507958.
  48. Corcoran, A.E., G.B. Richerson & M.B. Harris.  Functional link between the hypocretin and serotonin systems in the neural control of breathing and central chemosensitivity.  J Neurophysiol, 114(1):381-9, 2015. [PMID: 25878157] PMCID: PMC4507970.
  49. McGlashon, J.B., A. Kozlowski, M. Gorecki, C. Thirnbeck, K. Markan, M.E. Kotas, M.J. Potthoff, G.B. Richerson & M.P. Gillum.  Central serotonergic neurons activate and recruit thermogenic brown and beige fat and regulate glucose and lipid homeostasis. Cell Metabolism, 21(5):692-705, 2015. [PMID: 25955206] PMCID: PMC4565052.
  50. Massey, C.A., K.E. Iceman, S.L. Johansen, Y. Wu, M.B. Harris & George B. Richerson.  Isoflurane abolishes spontaneous firing of serotonin neurons and masks their pH/CO2 chemosensitivity. J Neurophysiol, 113(7):2879-88, 2015.  [PMID: 25695656] PMCID: PMC4416618.
  51. Richerson, G.B & L.M. Bateman.  Partners Against Mortality in Epilepsy Conference Summary. Epilepsy Currents, 14(6) Supplement:16-18, 2014.
  52. Brust, R.D., A.E. Corcoran, G.B. Richerson, E.E.Nattie, S.M. Dymecki. Functional and developmental identification of a molecular subtype of brain serotonergic neuron specialized to regulate breathing dynamics. Cell Reports, 9(6):2152-65, 2014. [PMID: 25497093] PMCID: PMC4351771.
  53. Cerpa, V.A. A. Gonzalez & G.B. Richerson. Diphtheria toxin treatment of Pet-1-Cre floxed diphtheria toxin receptor mice disrupts thermoregulation without affecting respiratory chemoreception. Neurosci, 279:65-76, 2014. [PMID: 25171790] PMCID: PMC4443915.
  54. Buchanan, G.F., N.M. Murray, M.A. Hajek & G.B. Richerson.  Serotonin neurones have anticonvulsant effects and reduce seizure-induced mortality. J Physiol, 592(19):4395-4410, 2014.  [PMID: 25107926] PMCID: PMC4215784.
  55. Massey, C.A., Sowers, L.P., Dlouhy, B.J. & G.B. Richerson.  Mechanisms of sudden unexpected death in epilepsy: the pathway to prevention.  Nature Rev Neurol, 10:271-282, 2014.  [PMID: 24752120] PMCID: PMC4565133.
  56. Teran, F.A., C.A. Massey & G.B. Richerson. Serotonin neurons and central respiratory chemoreception: Where are we now? Prog Brain Res, 209:207-233, 2014. [PMID: 24746050] PMCID: PMC4486262.
  57. Price, M.P., H. Gong, M.G. Parsons, J.R. Kundert, L.R. Reznikov, L. Bernardinelli, K. Chaloner, G.F. Buchanan, J.A. Wemmie, G.B. Richerson, M.D. Cassell & M.J. Welsh.   Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli. Genes Brain and Behavior, 13(2):179-94, 2014. [PMID: 24256442] PMCID: PMC3998777.
  58. Corcoran, A.E., K.G. Commons, J.C. Smith, M.B. Harris & G.B. Richerson. Dual effects of 5-HT1a receptor activation on breathing in neonatal mice. J Neurosci, 34(1):51-59, 2014. [PMID: 24381267] PMCID: PMC3866493.
  59. Iceman, K.E., M.B. Harris, G.B. Richerson.  Medullary serotonin neurons are CO2-sensitive in situ.  J Neurophysiol, 110(11):2536-44, 2013. [PMID: 24047906] PMCID: PMC3882770.
  60. Massey, C.A., G. Kim, A.E. Corcoran, R.L. Haynes, D.S. Paterson, K.J. Cummings, S.M. Dymecki, G.B. Richerson, E.E. Nattie, H.C. Kinney, and K.G. Commons. Development of brainstem 5-HT1A receptor binding sites in serotonin neuron-deficient mice.  J Neurochem, 126(6):749-57, 2013. [PMID: 23692315] PMCID: PMC3987866.
  61. Sowers, L.P., C.A. Massey, B.K. Gehlbach, M.A. Granner & G.B. Richerson. Sudden unexpected death in epilepsy: Fatal post-ictal respiratory and arousal mechanisms. Resp Physiol & Neurobiol, 189(2):315-23, 2013. [PMID: 23707877] PMCID: PMC4467545.
  62. Sowers, L.P., L. Loo, Y. Wu, E. Campbell, J.D. Ulrich, S. Wu, L. Paemka, T. Wassink, K. Meyer, X. Bing, H. El-Shanti, Y.M. Usachev, N. Ueno, R.J. Manak, A.J. Shepherd, P.J. Ferguson, G.B. Richerson, D.P. Mohapatra, J.A. Wemmie, A.G. Bassuk. Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction. Mol Psych, 18(10):1077-89, 2013. [PMID: 23711981] PMCID:  PMC4163749.
  63. Richerson, G.B. SUDEP – Serotonin: The Anti-SuddenDeathAmine?  Epilepsy Currents, 13(5):241-4, 2013. [PMID: 24348119] PMCID: PMC3854735.
  64. Richerson, G.B. PAME 2012: Summary of Session VI.  Epilepsy Currents, 13(2) Supplement:5-21, 2013. [PMID: 25484628] PMCID: PMC4242516.
  65. Corcoran, A.E., G.B. Richerson & M.B. Harris.  Serotonergic mechanisms are necessary for central respiratory chemoresponsiveness in situ. Resp Physiol & Neurobiol, 186(2):214-20, 2013. [PMID: 23454177] PMCID: PMC3645885.
  66. Ransom, C.B., W. Tao, Y. Wu, W.J. Spain & G.B. Richerson. Rapid regulation of tonic GABA currents in cultured rat hippocampal neurons.  J Neurophysiol, 109(3):803-12, 2013. [PMID: 23114210] PMCID: PMC3567397.
  67. Dymecki, S.M., Ray, R.R., Brust, R.D., Corcoran, A.E., Kim, J.C., Richerson, G.B., and Nattie, E. Response to Comment on “Impaired respiratory and body temperature control upon acute serotonergic neuron inhibition.” Science 337(6095): 646c, 2013. [PMID: 21798952] PMCID: PMC3729433.
  68. Ray, R., A. Corcoran, R. Brust, J. C. Kim, G.B. Richerson, E.E. Nattie & S. M. Dymecki. Homeostatic imbalance upon acute in vivo serotonergic neuron inhibition.  Science 333(6042): 637-642, 2011. [PMID: 21798952] PMCID: PMC3729433 (Science Editor’s Choice). (Faculty of 1000).
  69. Bravata D.M., Concato J, Fried T, Ranjbar N, Sadarangani T, McClain V, Struve F, Zygmunt L, Knight H.J., Lo A, Richerson G.B., Gorman M, Williams L.S., Brass L.M., Agostini J, Mohsenin V, Roux F, Yaggi H.K. Continuous positive airway pressure: Evaluation of a novel therapy for patients with acute ischemic stroke. Sleep 34(9):1271-77, 2011. [PMID: 21886365] PMCID: PMC3157669.
  70. Hodges, M.R., S. Best, G.B. Richerson. Altered ventilatory and thermoregulatory control in male and female adult Pet-1 null mice. Resp Physiol Neurobiol 177(2):133-40, 2011. [PMID: 21453797] PMCID: PMC4554716.
  71. Richerson, G.B. & G.F. Buchanan. The serotonin axis:  Shared mechanisms in seizures, depression, and SUDEP. Epilepsia 52 (Suppl 1):28-38, 2011. [PMID: 21214537] PMCID: PMC3052632.
  72. Buchanan, G.F. & G.B. Richerson. Central serotonin neurons are required for arousal to CO2. PNAS 107(37): 16354-9, 2010. [PMID: 20805497] PMCID: PMC2941296.
  73. Ransom, C.B. Y. Wu & G.B. Richerson. Postdepolarization Potentiation of GABAA Receptors: A Novel Mechanism Regulating Tonic Conductance in Hippocampal Neurons. J Neurosci 30(22):7672-7684, 2010. [PMID: 20519542] PMCID: PMC2902370.
  74. Bravata, D.M., J. Concato, T. Fried, N. Ranjbar, T. Sadarangani, V. McClain, F. Struve, L. Zygmunt, H.J. Knight, A.C. Lo, George B Richerson, Mark Gorman, Linda S. Williams, Lawrence M Brass, Joseph Agostini, Vahid Mohsenin, Francoise Roux, and H Klar Yaggi. Auto-Titrating Continuous Positive Airway Pressure for Patients With Acute Transient Ischemic Attack. A Randomized Feasibility Trial.  Stroke 41(7):1464-1470, 2010. [PMID: 20508184] NIHMS: 213418
  75. Hodges, M.R. & G.B. Richerson. Medullary serotonin neurons and their roles in central respiratory chemoreception. Respir Physiol Neurobiol 173(3): 256-263, 2010. [PMID: 20226279] PMCID: PMC4554718.
  76. Richerson, G.B. Respiratory plasticity in sleep apnoea: Should it be harnessed or restrained? J Physiol 588(1):3-4, 2010. [PMID: 20045895] PMCID: PMC2821532.
  77. Hodges, M.R. & G.B. Richerson. The role of medullary serotonin (5-HT) neurons in respiratory control: contributions to eupneic ventilation, CO2 chemoreception, and thermoregulation. J Appl Physiol 108(5):1425-1432, 2010. [PMID: 20133432] PMCID: PMC2867541.
  78. Corcoran, A., G. Richerson & M. Harris. Modulation of respiratory activity by hypocretin-1 (orexin A) in situ and in vitro. Adv Exp Biol Med 669: 109-13, 2010. [PMID: 20217331] NIHMS: 212681
  79. Hodges, M.R., M. Wehner, J. Aungst, J.C. Smith & G.B. Richerson. Transgenic mice lacking serotonin neurons have severe apnea and high mortality during development. J Neurosci 29(33):10341-10349, 2009. [PMID: 19692608] PMCID: PMC2755228.
  80. Corcoran, A.E., M.R. Hodges, Y. Wu, W. Wang, C.J. Wylie, E.S. Deneris and G.B. Richerson. Medullary serotonin neurons and central CO2 chemoreception. Respir Physiol Neurobiol 168:49-58, 2009. [PMID: 19394450] PMCID: PMC2787387.
  81. Buchanan, G.F. & G.B. Richerson. Role of chemoreceptors in mediating dyspnea. Respir Physiol Neurobiol 167(1):9-19, 2009. [PMID: 19118649] PMCID: PMC4486073.
  82. Ptak, K., T. Yamanishi, J. Aungst, L.S. Milescu, R. Zhang, G.B. Richerson & J.C. Smith. Raphé neurons stimulate respiratory circuit activity by multiple mechanisms via endogenously released serotonin and substance P. J Neurosci 29(12): 3720-37, 2009. PMCID: PMC2940110.
  83. Kinney, H.C., G.B. Richerson, S.M. Dymecki, R.A. Darnall & E.E. Nattie. The brainstem and serotonin in the sudden infant death syndrome. Annual Rev Pathol 4: 517-550, 2009. [PMID: 19400695] PMCID: PMC3268259.
  84. Hodges, M.R. & G.B. Richerson.  Contributions of 5-HT neurons to respiratory control: Neuromodulatory and trophic effects. Respir Physiol Neurobiol 164: 222-232, 2008. [PMID: 18595785] PMCID: PMC2576037.
  85. Hodges, M.R. & G.B. Richerson. Interaction between defects in ventilatory and thermoregulatory control in mice with near-complete absence of 5-HT neurons. Respir Physiol Neurobiol 164:350-357, 2008. [PMID: 18775520] PMCID: PMC2613046. 
  86. Johnson, S.M., M.A. Haxhiu & G.B. Richerson. GFP expressing Locus Coeruleus neurons from Prp57 transgenic mice exhibit differential CO2/H+ responses in primary cell culture. J Appl Physiol 105(4):1301-11, 2008. [PMID:18635881] PMCID: PMC2576037.
  87. Hodges, M.R., G.J. Tattersall, M.B. Harris, S.D. McEvoy, D.N. Richerson, E.S. Deneris, R.L. Johnson, Z.F. Chen & G.B. Richerson. Defects in breathing and thermoregulation in mice with near-complete absence of central serotonin neurons. J Neurosci 28(10): 2495-2505, 2008. [PMID: 18322094] PMCID: PMC6671195.
  88. Wu, Y., W. Wang, A. Diez-Sampedro & G.B. Richerson. Nonvesicular inhibitory neurotransmission via reversal of the GABA transporter GAT-1. Neuron 56(5): 851-65, 2007. [PMID: 18054861] PMCID: PMC2156040.
  89. Wang, W. & G.B. Richerson.  Changes in glucose do not alter baseline firing rate or chemosensitivity of serotonin neurons cultured from the medullary raphé. Respir Physiol Neurobiol 157(2-3):235-41, 2007. [PMID:17336599]
  90. Wu, Y., W. Wang & G.B. Richerson.  The transmembrane sodium gradient influences ambient GABA concentration by altering the equilibrium of GABA transporters. J Neurophysiol 96: 2425-2436, 2006. [PMID: 16870837]
  91. Diez-Sampedro, A., W.R. Silverman, J.F. Bautista & G.B. Richerson. Mechanism of increased open probability by a mutation of the BK channel.  J Neurophysiol 96: 1507-1516, 2006. [PMID:1673821].
  92. Du, W., J.F. Bautista, H. Yang, A. Diez-Sampedro, S.A. You, L. Wang, P. Kotagal, H.O. Lüders, J. Shi, J. Cui, G.B. Richerson & Q. Wang. Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder.  Nature Genetics 37(7): 733-738, 2005. [PMID: 1593747].
  93. Richerson, G.B., W. Wang, M.R. Hodges, C.I. Dohle & A. Diez-Sampedro. Homing in on the specific phenotype(s) of central respiratory chemoreceptors. Exp Physiol 90(3): 259-269, 2005. [PMID: 15728134].
  94. Richerson, G.B., W. Wang, M.R. Hodges, C.I. Dohle & A. Diez-Sampedro. Commentary on “Retrotrapezoid nucleus: a litmus test for the identification of central chemoreceptors.” Exp Physiol 90(3): 247-257, 2005. [PMID: 15728134].
  95. Richerson, G.B. Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nature Reviews Neuroscience 5:449-461, 2004. [PMID: 15152195].
  96. Bouyer, P., S. Risso Bradley, J. Zhao, W. Wang, G.B. Richerson & W.F. Boron. Effect of extracellular acid-base disturbances on the intracellular pH of neurons cultured from rat medullary raphé or hippocampus. J Physiol (Lond) 559:85-101, 2004. [PMID:15194736] PMCID: PMC1665070.
  97. Richerson, G.B.  Looking for GABA in all the wrong places: The relevance of extrasynaptic GABAA receptors to epilepsy. Epilepsy Currents 4(6): 239-242, 2004. [PMID: 16059513] PMCID: PMC1176385.
  98. Richerson, G.B. & J.M. Bekkers. Learning to take a deep breath – with BDNF.  Nature Medicine 10(1):25-26, 2004. [PMID: 14702628].
  99. Nattie, E.E., A. Li, G. Richerson & D.A. Lappi. Medullary serotonergic neurons and adjacent neurons that express neurokinin-1 receptors are both involved in chemoreception in vivo. J Physiol (Lond) 556(1): 235-253, 2004. [PMID: 14724193] PMCID: PMC1664900.
  100. Richerson, G.B. & Y. Wu. Role of the GABA transporter in epilepsy. Adv Exp Med Biol 548: 76-91, 2004. [PMID:15250587].
  101. Severson, C.A., W. Wang, V.A. Pieribone, C.I. Dohle & G.B. Richerson. Midbrain serotonergic neurons are central pH chemoreceptors. Nature Neurosci 6(11):1139-1140, 2003. [PMID: 14517544].
  102. Richerson, G.B. & Y. Wu. Dynamic equilibrium of neurotransmitter transporters: not just for reuptake anymore. J Neurophysiol  90:1363-1374, 2003. [PMID: 12966170] PMCID: PMC12966170.
  103. Wu, Y., W. Wang & G.B. Richerson. Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release. J Neurophysiol 89(4): 2021-2034, 2003. [PMID: 12612025].
  104. Bradley, S. Risso, V. A. Pieribone, W. Wang, C.A. Severson, R. A. Jacobs & G. B. Richerson. Chemosensitive serotonergic neurons are closely associated with large medullary arteries. Nature Neurosci 5(5): 401-402, 2002. [PMID: 11967547].
  105. Wang, W., S. Risso Bradley & G.B. Richerson. Quantification of the response of rat medullary raphe neurones to independent changes in pHo and PCO2. J Physiol (Lond) 540(3): 951-970, 2002. [PMID: 11986382] PMCID: 2290275.
  106. Wu, Y., W. Wang & G.B. Richerson.  GABA transaminase inhibition induces spontaneous and enhances depolarization-evoked GABA efflux via reversal of the GABA transporter.  J Neurosci 21(8):2630-2639, 2001. [PMID: 11306616] PMCID: PMC6762542.
  107. Wang, W., J.K. Tiwari, S. Risso Bradley, A.V. Zaykin & G.B. Richerson. Acidosis-stimulated neurons of the medullary raphe are serotonergic.  J Neurophysiol 85:2224-2235, 2001. [PMID: 11353037].
  108. Richerson, G.B., W. Wang, J.K. Tiwari & S. Risso Bradley. Chemosensitivity of serotonergic neurons in the rostral ventral medulla.  Respir Physiol 129: 175-189, 2001.
  109. Bautista, J., E. Wyllie & G.B. Richerson.  Refractory seizures in a 17-year-old: Re-evaluating therapy. NeuroNetwork 2(1):2-3, 2000.
  110. Wang, W., & G.B. Richerson.  Chemosensitivity of nonrespiratory rat neurons in primary tissue culture.  Brain Research 860:119-129, 2000. [PMID: 10727630].
  111. Wang, W., G.B. Richerson. Development of chemosensitivity of rat medullary raphe neurons. Neurosci 90(3):1001-1011, 1999. [PMID: 10218799].
  112. Wang, W., J. Pizzonia, & G.B. Richerson. Chemosensitivity of rat medullary raphe neurones in primary tissue culture.  J Physiol (Lond) 511(2):433-450, 1998. [PMID: 9706021] PMCID: PMC2231124.
  113. Gaspary, H., W. Wang, & G.B. Richerson. Carrier-mediated GABA release induces GABA receptor conductances in hippocampal neurons. J Neurophysiol 80:270-281, 1998. [PMID: 9658049].
  114. Richerson, G.B.  Sudden Infant Death: The role of central chemosensitivity.  Neuroscientist 3(1):309-313, 1997.
  115. Richerson, G.B. & H.L. Gaspary. Carrier-mediated GABA release: Is there a functional role? Neuroscientist 3(3):151-157, 1997.
  116. Richerson, G.B.  Chloride: An anaplastic anion?  Neuroreport 7:969-970, 1996. [PMID: 8804032].
  117. Richerson, G.B.  Response to CO2 of neurons in the rostral ventral medulla in vitro.  J Neurophysiol 73(3):933-944, 1995. [PMID: 7608778].
  118. Honmou, O., J.D. Kocsis & G.B. Richerson. Gabapentin potentiates the conductance increase induced by nipecotic acid in CA1 pyramidal neurons in vitro. Epi Res 20:193-202, 1995. [PMID: 7796791] NIHMSID: NIHMS80526.
  119. Richerson, G.B. & C. Messer. Effect of composition of experimental solutions on neuronal survival during rat brain slicing.  Exp Neurol 131:133-143, 1995. [PMID:7895807].
  120. Oyelese, A.A., D.L. Eng, G.B. Richerson & J.D. Kocsis.  Nerve injury enhances GABAA receptor mediated conductances in a subclass of sensory neurons. J Neurophysiol 74(2):673-683, 1995. [PMID: 7472373] PMCID: PMC2605359.
  121. Richerson, G.B. & P.A. Getting.  Medullary respiratory neurons in the guinea pig.  Localization and firing patterns.  Brain Res 591:79-87, 1992. [PMID:1446235].
  122. Bekkers, J.M., G.B. Richerson & C.F. Stevens. Origin of variability in quantal size in cultured hippocampal neurons and hippocampal slices.  PNAS 87:5359-5362, 1990. [PMID: 2371276] PMCID: PMC54323.
  123. Richerson, G.B. & P.A. Getting. Preservation of integrative function in a perfused guinea pig brain.  Brain Res 517:7-18, 1990. [PMID: 2376008].
  124. Richerson, G.B. & P.A. Getting. Maintenance of complex neural function during perfusion of the mammalian brain.  Brain Res 409:128-132, 1987. [PMID: 2376008].
  125. Richerson, G.B. The respiratory centers of the guinea pig: In vivo and perfused brain studies. Ph.D. Dissertation.  May 1987.
  126. Dekin, M.S., G.B. Richerson & P.A. Getting.  Thyrotropin-releasing hormone induces rhythmic bursting in neurons of the nucleus tractus solitarius.  Science 229:67-69, 1985. [PMID: 3925552].

* - Authors contributed equally to the work.

Book Chapters

  1. Teran, F.A. & G.B. Richerson. 5-HT neurons and central CO2 chemoreception. In: Handbook of the Behavioural Neurobiology of Serotonin. Edited by C.P. Muller & K.A. Cunningham. Elsevier, Amsterdam, 2019.
  2. Buchanan, G.F. & G.B. Richerson. Current evidence for a role of serotonin in SUDEP. In: Sudden unexpected death in epilepsy: a global conversation, eds. D. Chapman, B. Moss, R. Panelli, and R. Pollard, Epilepsy Australia Ltd, Camberwell, Victoria, 2018.
  3. Teran, F.A., C.A. Massey & G.B. Richerson. Overview of Section on Current Research on Causes of SUDEP. In: Sudden unexpected death in epilepsy: a global conversation, eds. D. Chapman, B. Moss, R. Panelli, and R. Pollard, Epilepsy Australia Ltd, Camberwell, Victoria, 2018 edition.
  4. Buchanan, G.F. & G.B. Richerson. Current evidence for a role of serotonin in SUDEP. In: Sudden unexpected death in epilepsy: a global conversation, eds. D. Chapman, B. Moss, R. Panelli, and R. Pollard, Epilepsy Australia Ltd, Camberwell, Victoria, 2015.
  5. Massey, C.A. & G.B. Richerson. Overview of Section on Current Research on Causes of SUDEP. In: Sudden unexpected death in epilepsy: a global conversation, eds. D. Chapman, B. Moss, R. Panelli, and R. Pollard, Epilepsy Australia Ltd, Camberwell, Victoria, 2015.
  6. Richerson, G.B. & W.F Boron.  Control of ventilation.  In: Textbook of Medical Physiology, 3rd Edition, Edited by Boulpaep, E. and W.F. Boron . WB Saunders, Co, New York, NY. 2013.
  7. Richerson, G.B.  The autonomic nervous system.  In: Textbook of Medical Physiology, 3rd Edition, Edited by Boulpaep, E. and W.F. Boron . WB Saunders, Co, New York, NY. 2013.
  8. Dyken, M.E., G.B. Richerson & C.L. Glenn. Obstructive sleep apnea associated with cerebral hypoxemia.  In Chokroverty Atlas of Sleep Medicine, 2013.
  9. Dyken, M.E., K.B. Im, G.B. Richerson & D.C. Lin-Dyken. Sleep and stroke, in Oxford Textbook of Sleep Disorders, ed by S Chokroverty & L Ferini-Strambi, 2017. Oxford University Press.
  10. Richerson, G.B., G. Aston-Jones & C.B. Saper.  Brainstem modulation of brain function.  In: Principles of Neural Science, Fifth edition.  Edited by Kandel, E.R., J.H. Schwartz, T.M. Jessel, A.J. Hudspeth & S.A. Siegelbaum, 2012.
  11. Saper, C.B., G.B. Richerson & A. Lumsden.  The brainstem and cranial nerves.  In: Principles of Neural Science, Fifth edition.  Edited by Kandel, E.R., J.H. Schwartz, T.M. Jessel, A.J. Hudspeth & S.A. Siegelbaum, 2012.
  12. Dyken, M.E., G.B. Richerson & K.B. Im.  Sleep Apnea, Stroke Risk Factors and the Arousal Response. In: Sleep, Stroke, and Cardiovascular Disease. Edited by Culebras, A. Cambridge Univ Press, 2013
  13. Buchanan, G.F. and G.B. Richerson. The role of the neurotransmitter serotonin in SUDEP. In: Sudden unexpected death in epilepsy: a global conversation, eds. D. Chapman, B. Moss, R. Panelli, and R. Pollard, Epilepsy Australia Ltd, Camberwell, Victoria, 2011.
  14. Ransom, C.B. & G.B. Richerson. GABA transporters: Regulation of tonic inhibition. In: Encyclopedia of Basic Epilepsy Research. Edited by P.A. Schwartzkroin.  Elsevier, Oxford, UK. 3:1380-1388, 2009.
  15. Ransom, C.B. & G.B. Richerson. GABA transporters as targets of antiepileptic drugs. In: Encyclopedia of Basic Epilepsy Research. Edited by P.A. Schwartzkroin.  Elsevier, Oxford, UK. 1:66-74, 2009.
  16. Dohle, C.I. & G.B. Richerson. 5-HT neurons and central CO2 chemoreception. In: The Behavioural Neurobiology of Serotonin. Edited by C.P. Muller & B.L. Jacobs. Elsevier, Amsterdam, 2009.
  17. Richerson, G.B. & W.F Boron.  Control of ventilation.  In: Textbook of Medical Physiology, 2nd Edition, Edited by Boulpaep, E. and W.F. Boron . WB Saunders, Co, New York, NY. 2009.
  18. Richerson, G.B.  The autonomic nervous system.  In: Textbook of Medical Physiology, 2nd Edition, Edited by Boulpaep, E. and W.F. Boron . WB Saunders, Co, New York, NY. 2009.
  19. Richerson, G.B.  Medullary raphe nuclei and respiratory control. In: Encyclopedia of Neuroscience. Edited by Binder, M.D., N. Hirokawa, & U. Windhorst, M.C. Hirsch. Springer-Verlag, Heidelberg, Germany. 2008.
  20. Buchanan, G.F., Hodges, M.R. & G.B. Richerson. Contribution of chemosensitive 5-HT neurons to interactions between the sleep/wake cycle and respiratory control. In: Serotonin and Sleep: Molecular, Functional and Clinical Aspects. Edited by Monti, J.M., S.R. Pandi-Perumal, B.L. Jacobs & D. Nutt. Birkhauser Verlag AG, Basel, Switzerland. 2008.
  21. Richerson, G.B. & W.F Boron.  Control of ventilation.  In: Textbook of Medical Physiology, Edited by Boulpaep, E. and W.F. Boron . WB Saunders, Co, New York, NY. 2002.
  22. Richerson, G.B.  The autonomic nervous system.  In: Textbook of Medical Physiology, Edited by Boulpaep, E. and W.F. Boron . WB Saunders, Co, New York, NY. 2002.
  23. Richerson, G.B.  pH effects on respiratory neurons.  in pH and Brain Function.  edited by Kaila, K., & B.R. Ransom.  John Wiley & Sons, New York, NY. 1998.